The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 28, 2017
Filed:
May. 13, 2013
Applicant:
Bayer As, Oslo, NO;
Inventors:
Hanne Therese Bonge-Hansen, Oslo, NO;
Olav Benjamin Ryan, Oslo, NO;
Assignee:
BAYER AS, Oslo, NO;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 103/40 (2006.01); A61K 51/10 (2006.01); A61P 35/00 (2006.01); A61K 51/04 (2006.01); C07K 16/32 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 51/0474 (2013.01); A61K 51/0455 (2013.01); A61K 51/0478 (2013.01); A61K 51/1027 (2013.01); A61K 51/1093 (2013.01); C07K 16/32 (2013.01); A61K 2039/505 (2013.01); C07K 2317/24 (2013.01);
Abstract
A tissue-targeting complex comprising a tissue targeting moiety, an octadentate hydroxypyridinone-containing ligand comprising four HOPO moieties and the ion of an alpha-emitting thorium radionuclide, where at least one of the four HOPO moieties is substituted at the N-position with a hydroxyalkyl solubilising group.