The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 28, 2017
Filed:
Oct. 24, 2014
Applicant:
The United States of America As Represented BY the Secretary of the Department of Health and Human Services, Washington, DC (US);
Inventors:
Michael J. Iadarola, Washington, DC (US);
Zoltan Olah, Szeged, HU;
Laszlo Karai, Miami Beach, FL (US);
Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/357 (2006.01); A61K 31/16 (2006.01); A61K 31/165 (2006.01); A61K 31/167 (2006.01);
U.S. Cl.
CPC ...
A61K 31/357 (2013.01); A61K 31/16 (2013.01); A61K 31/165 (2013.01); A61K 31/167 (2013.01);
Abstract
The present invention provides methods and kits for the selective ablation of pain-sensing neurons. The methods comprise administration of a vanilloid receptor agonist to a ganglion in an amount that causes death of vanilloid receptor-bearing neurons. Accordingly, the present invention provides methods of controlling pain and inflammatory disorders that involve activation of vanilloid receptor-bearing neurons.