logo

For the Inventor, By the Inventor

The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9827187 B1

PDFFull Text
Date of Patent:
Nov. 28, 2017

Filed:

Mar. 29, 2013

Filaggrin gene expression promoter

Applicant:

Shiseido Company, Ltd., Chuo-ku, Tokyo, JP;

Inventors:

Yoko Gozu, Yokohama, JP;

Shinichiro Haze, Yokohama, JP;

Assignee:

Shiseido Company, Ltd., Tokyo, JP;

Attorney:

Foley & Lardner LLP

Primary Examiner:

Qiuwen Mi

Int. Cl.
CPC ...
A61K 36/00 (2006.01); A61K 8/97 (2017.01); A61Q 19/00 (2006.01); A61K 31/235 (2006.01); A61K 31/245 (2006.01); A61K 36/23 (2006.01); A61K 36/53 (2006.01); A61K 36/73 (2006.01); A61K 8/44 (2006.01); A61K 8/92 (2006.01); A61K 36/758 (2006.01); A61K 36/14 (2006.01); A61K 36/185 (2006.01); A61K 36/67 (2006.01); A61K 9/00 (2006.01); A61K 47/10 (2017.01); A61K 47/14 (2017.01); A61K 9/06 (2006.01); A61K 47/44 (2017.01); A61K 9/20 (2006.01); A61K 9/50 (2006.01); A61K 8/37 (2006.01); A61K 8/41 (2006.01); A61K 8/49 (2006.01);
U.S. Cl.
CPC ...
A61K 8/97 (2013.01); A61K 8/37 (2013.01); A61K 8/411 (2013.01); A61K 8/44 (2013.01); A61K 8/445 (2013.01); A61K 8/4926 (2013.01); A61K 8/922 (2013.01); A61K 9/0014 (2013.01); A61K 9/06 (2013.01); A61K 9/2018 (2013.01); A61K 9/2068 (2013.01); A61K 9/5042 (2013.01); A61K 31/235 (2013.01); A61K 31/245 (2013.01); A61K 36/14 (2013.01); A61K 36/185 (2013.01); A61K 36/23 (2013.01); A61K 36/53 (2013.01); A61K 36/67 (2013.01); A61K 36/73 (2013.01); A61K 36/758 (2013.01); A61K 47/10 (2013.01); A61K 47/14 (2013.01); A61K 47/44 (2013.01); A61Q 19/00 (2013.01); A61Q 19/007 (2013.01); A61K 2800/70 (2013.01); A61K 2800/74 (2013.01);
Abstract

The present invention provides a novel substance that promotes expression of filaggrin gene involved in improvement of the moisture retention function of skin. The inventors of the present invention found that expression of filaggrin gene fluctuates rhythmically over a roughly 24 hour cycle, screened candidate substances based on the time at which expression reaches a maximum following addition of the candidate substance, and identified zanthoxylum extract, 3-(1'-piperidine)propionic acid, geranium oil, cypress oil, rose oil, galvanum oil, pepper oil, basil oil, methyl-o-toluate, methyl anthranilate and dimethyl anthranilate as filaggrin gene expression promoting agents.

Find Patent Forward Citations

Loading…