The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 21, 2017
Filed:
May. 15, 2015
Applicant:
The Regents of the University of California, Oakland, CA (US);
Inventors:
Elizabeth A. Znameroski, Berkeley, CA (US);
James H. Doudna Cate, Berkeley, CA (US);
N. Louise Glass, Orinda, CA (US);
Assignee:
The Regents of the University of California, Oakland, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/80 (2006.01); C12N 9/04 (2006.01); C12N 9/18 (2006.01); C12N 9/24 (2006.01); C12N 9/42 (2006.01); C12P 19/02 (2006.01); C12P 19/14 (2006.01); C12P 21/00 (2006.01);
U.S. Cl.
CPC ...
C12N 15/80 (2013.01); C12N 9/0006 (2013.01); C12N 9/18 (2013.01); C12N 9/24 (2013.01); C12N 9/2402 (2013.01); C12N 9/2437 (2013.01); C12N 9/2445 (2013.01); C12P 19/02 (2013.01); C12P 19/14 (2013.01); C12P 21/00 (2013.01); C12Y 302/01021 (2013.01); C12Y 101/99018 (2013.01); C12Y 302/01004 (2013.01);
Abstract
The present disclosure provides mutant cells for the secretion of proteins and for the degradation of lignocellulosic biomass. Methods for the use of these cells are also provided. Specifically, the utility of combined genetic deletions of β-glucosidases and the catabolite repressor gene creA/cre-1 for protein secretion in fungal and yeast cells is disclosed.