The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 21, 2017

Filed:

May. 13, 2015
Applicant:

The Board of Trustees of the Leland Stanford Junior University, Stanford, CA (US);

Inventors:

Marius Wernig, Stanford, CA (US);

Thomas C. Sudhof, Stanford, CA (US);

Thomas Vierbuchen, Stanford, CA (US);

Austin Ostermeier, West Plains, MO (US);

Zhiping Pang, Stanford, CA (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 5/0797 (2010.01); C12N 5/071 (2010.01); C12Q 1/68 (2006.01); C12N 5/0793 (2010.01); C12N 5/079 (2010.01); G01N 33/50 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0619 (2013.01); C12N 5/0622 (2013.01); C12N 5/0623 (2013.01); G01N 33/5058 (2013.01); C12N 2501/60 (2013.01); C12N 2506/02 (2013.01); C12N 2506/1307 (2013.01); C12N 2506/14 (2013.01); C12N 2506/45 (2013.01); C12N 2510/00 (2013.01);
Abstract

Methods, compositions and kits for producing functional neurons, astroctyes, oligodendrocytes and progenitor cells thereof are provided. These methods, compositions and kits find use in producing neurons, astrocytes, oligodendrocytes, and progenitor cells thereof for transplantation, for experimental evaluation, as a source of lineage- and cell-specific products, and the like, for example for use in treating human disorders of the CNS. Also provided are methods, compositions and kits for screening candidate agents for activity in converting cells into neuronal cells, astrocytes, oligodendrocytes, and progenitor cells thereof.


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