The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 21, 2017

Filed:

May. 30, 2014
Applicants:

Dong-a Socio Holdings Co., Ltd., Seoul, KR;

Dong-a St Co., Ltd, Seoul, KR;

Inventors:

Hyounmie Doh, Seoul, KR;

Byong Moon Kim, Seoul, KR;

Chae Young Kim, Suwon-si, KR;

Sung-Hee Lee, Seoul, KR;

Dong-Hyeon Kim, Daejeon, KR;

Yoo-jin Kim, Yongin-si, KR;

Dongsop Lee, Yongin-si, KR;

Kyung Mi Han, Yongin-si, KR;

Dongsup Song, Suwon-si, KR;

Eun-ee Jung, Seoul, KR;

Jinseok Lee, Suwon-si, KR;

Woo Jin Seung, Seoul, KR;

Kyusang Hwang, Seoul, KR;

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/22 (2006.01); A61K 39/395 (2006.01); C07K 16/30 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/22 (2013.01); A61K 39/3955 (2013.01); C07K 16/30 (2013.01); A61K 2039/505 (2013.01); C07K 2317/24 (2013.01); C07K 2317/33 (2013.01); C07K 2317/54 (2013.01); C07K 2317/55 (2013.01); C07K 2317/565 (2013.01); C07K 2317/622 (2013.01); C07K 2317/73 (2013.01); C07K 2317/76 (2013.01);
Abstract

A novel anti-vascular endothelial growth factor (VEGF) antibody having a strong binding affinity for VEGF and capable of inhibiting in vivo tumor growth and a composition for the treatment of cancer, containing the same. The antibody shows a remarkable binding property to human and mouse VEGF, suppresses the proliferation and permeability of a human umbilical vein endothelial cell (HUVEC) and inhibits tumor growth, and thus can be useful as an antibody for the treatment of cancer.


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