The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 21, 2017
Filed:
Dec. 01, 2014
Applicant:
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Inventors:
Allison D. Ortigosa, Harrisonburg, VA (US);
William Perry, Longmont, CO (US);
Mark C. Sleevi, Longmont, CO (US);
Luis Sierra, Dunellen, NJ (US);
Assignee:
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 1/30 (2006.01); C07K 14/62 (2006.01); C07K 1/113 (2006.01);
U.S. Cl.
CPC ...
C07K 14/62 (2013.01); C07K 1/1136 (2013.01); C07K 1/306 (2013.01); C07B 2200/13 (2013.01);
Abstract
A method for crystallizing insulin or insulin analogs under alkaline conditions and purifying the insulin or insulin analog crystals by filtering through a filter and drying the insulin or insulin analog crystals captured on the filter to produce crystalline insulin or insulin analog crystal compositions is described. In particular aspects, the method may be used to crystalize insulin glargine.