The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 21, 2017
Filed:
Aug. 04, 2016
Applicant:
Apicore Us Llc, Somerset, NJ (US);
Inventors:
Ravishanker Kovi, Monroe, NJ (US);
Jayaraman Kannapan, Gujarat, IN;
Vasanthakumar G Ramu, Karnataka, IN;
Alaparthi Lakshmi Prasad, Vadodara, IN;
Talluri Bhushaiah Chowdary, Tenali, IN;
Gaurav Kulkarni, Gujarat, IN;
Saiyed Akeel Ahmed Shakeel Ahmed, Vadodara, IN;
Veerabhadra Rao Bobbili, Andhra Pradesh, IN;
N V Raghavalu Dusanapudi, Andhra Pradesh, IN;
Anand V. Mantri, Vadodara, IN;
Assignee:
Apicore US LLC, Somerset, NJ (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); C07K 5/00 (2006.01); C07K 7/00 (2006.01); C07K 16/00 (2006.01); C07K 17/00 (2006.01); C07K 5/107 (2006.01); C07K 5/065 (2006.01);
U.S. Cl.
CPC ...
C07K 5/1016 (2013.01); C07K 5/06078 (2013.01);
Abstract
Racemization-free methods are disclosed for the synthesis of carfilzomib. Novel intermediates and methods of making carfilzomib employing fragment condensation using the novel intermediates are disclosed. Amorphous carfilzomib and methods of making same are disclosed.