The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 21, 2017

Filed:

Nov. 13, 2013
Applicant:

Array Biopharma Inc., Boudler, CO (US);

Inventors:

Shelley Allen, Boulder, CO (US);

Barbara J. Brandhuber, Boulder, CO (US);

Kevin Ronald Condroski, San Diego, CA (US);

Lily Huang, Austin, TX (US);

Timothy Kercher, San Diego, CA (US);

Shannon L. Winski, Boulder, CO (US);

Assignee:

Array BioPharma Inc., Boulder, CO (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); C07D 231/56 (2006.01); C07D 471/04 (2006.01); C07D 491/048 (2006.01); C07D 495/04 (2006.01); C07D 403/12 (2006.01); C07D 519/00 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); C07D 231/56 (2013.01); C07D 403/12 (2013.01); C07D 471/04 (2013.01); C07D 491/048 (2013.01); C07D 495/04 (2013.01); C07D 519/00 (2013.01);
Abstract

Compounds of Formula I or stereoisomers, tautomers, or pharmaceutically acceptable salts, solvates or prodrugs thereof, wherein Ring A, Ring C and X are as defined herein, are inhibitors of TrkA kinase and are useful in the treatment of diseases which can be treated with a TrkA kinase inhibitor such as pain, cancer, inflammation/inflammatory diseases, neurodegenerative diseases, certain infectious diseases, Sjogren's syndrome, endometriosis, diabetic peripheral neuropathy, prostatitis and pelvic pain syndrome.


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