The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 21, 2017

Filed:

Dec. 18, 2014
Applicants:

Brian M. Andresen, Boston, MA (US);

Kenneth L. Arrington, Lansdale, PA (US);

Ryan D. Otte, Boston, MA (US);

John Michael Ellis, Boston, MA (US);

John W. Butcher, Berlin, MA (US);

Alan B. Northrup, Boston, MA (US);

Joel S. Robichaud, Dollard-des-Ormeaux, CA;

Jacques Yves Gauthier, Laval des Rapides, CA;

Jean-francois Fournier, Juan les Pins, FR;

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Inventors:

Brian M. Andresen, Sharon, MA (US);

Kenneth L. Arrington, Lansdale, PA (US);

Ryan D. Otte, Natick, MA (US);

John Michael Ellis, Needham, MA (US);

John W. Butcher, Berlin, MA (US);

Alan B. Northrup, Reading, MA (US);

Joel S. Robichaud, Dollard-des-Ormeaux, CA;

Jacques Yves Gauthier, Laval des Rapides, CA;

Jean-Francois Fournier, Juan les Pins, FR;

Assignees:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Merck Canada Inc., Kirkland, Quebec, CA;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 417/12 (2006.01); C07D 417/14 (2006.01); A61K 31/506 (2006.01); A61K 31/5377 (2006.01); A61K 31/538 (2006.01);
U.S. Cl.
CPC ...
C07D 417/14 (2013.01); A61K 31/506 (2013.01); A61K 31/538 (2013.01); A61K 31/5377 (2013.01); C07D 417/12 (2013.01);
Abstract

The invention provides certain thiazole-substituted aminoheteroaryl compounds of the Formula (I) or pharmaceutically acceptable salts thereof, wherein ring R, R, R, R, ring B, and the subscript r are as defined herein. The invention also provides pharmaceutical compositions comprising such compounds, and methods of using the compounds for treating diseases or conditions mediated by Spleen Tyrosine Kinase (Syk).


Find Patent Forward Citations

Loading…