The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 21, 2017

Filed:

Oct. 07, 2014
Applicant:

Novartis Ag, Basel, CH;

Inventors:

Claus Ehrhardt, Lorrach, DE;

Leslie Wighton McQuire, Warren, NJ (US);

Pascal Rigollier, Hagenthal-le-Bas, FR;

Olivier Rogel, Hesingue, FR;

Michael David Shultz, Lexington, MA (US);

Ruben Alberto Tommasi, Stow, MA (US);

Assignee:

NOVARTIS AG, Basel, CH;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/402 (2006.01); C07D 207/30 (2006.01); C07D 333/22 (2006.01); A61K 31/381 (2006.01); C07D 213/50 (2006.01); A61K 31/4409 (2006.01); C07D 231/56 (2006.01); A61K 31/416 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07D 333/22 (2013.01); A61K 31/381 (2013.01); A61K 31/402 (2013.01); A61K 31/416 (2013.01); A61K 31/4409 (2013.01); A61K 45/06 (2013.01); C07D 207/30 (2013.01); C07D 213/50 (2013.01); C07D 231/56 (2013.01);
Abstract

The present invention provides a compound of formula (I): said compound is inhibitor of MMP-2, and/or MMP-8, and/or MMP-9, and/or MMP-12 and/or MMP-13, and thus can be employed for the treatment of a disorder or disease characterized by abnormal activity of MMP-2, and/or MMP-8, and/or MMP-9, and/or MMP-12 and/or MMP-13. Accordingly, the compound of formula (I) can be used in treatment of disorders or diseases mediated by MMP-2, and/or MMP-8, and/or MMP-9, and/or MMP-12, and/or MMP-13. Finally, the present invention also provides a pharmaceutical composition.


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