The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 21, 2017
Filed:
Feb. 27, 2015
Applicant:
Oxford University Innovation Limited, Oxford, GB;
Inventors:
David Vaux, Oxford, GB;
Letitia Jean, Oxford, GB;
Stephen Davies, Oxford, GB;
Angela Russell, Oxford, GB;
Graham Wynne, Oxford, GB;
Carole Bataille, Oxford, GB;
Méabh Brennan, London, GB;
Assignee:
Oxford University Innovation Limited, Oxford, GB;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 215/00 (2006.01); C07D 215/26 (2006.01); C07D 413/14 (2006.01); C07D 401/06 (2006.01); A61K 31/47 (2006.01); A61K 31/4709 (2006.01); A61K 31/5377 (2006.01); C07D 405/06 (2006.01);
U.S. Cl.
CPC ...
C07D 215/26 (2013.01); A61K 31/47 (2013.01); A61K 31/4709 (2013.01); A61K 31/5377 (2013.01); C07D 401/06 (2013.01); C07D 405/06 (2013.01); C07D 413/14 (2013.01);
Abstract
The present invention relates to quinoline compounds as defined by Formula I below. Such quinoline compounds have been shown to inhibit the formation of amyloid deposits (e.g., amyloid oligomers, fibrils or plaques). Consequently, these compounds are suitable for treating a range of diseases and disorders in which amyloid deposits are implicated, such as type-2 diabetes and Alzheimer's disease.