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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9822076 B1

PDFFull Text
Date of Patent:
Nov. 21, 2017

Filed:

Oct. 12, 2016

Kinase inhibitor

Applicants:

Respivert Limited, High Wycombe, GB;

Topivert Pharma Limited, London, GB;

Inventor:

Matthew Colin Thor Fyfe, London, GB;

Assignees:

Respivert Limited, High Wycombe, Buckinghamshire, GB;

Topivert Pharma Limited, London, GB;

Attorney:

Knobbe, Martens Olson & Bear, LLP

Primary Examiner:

Zinna Northington Davis

Int. Cl.
CPC ...
C07D 213/74 (2006.01); A61K 31/4412 (2006.01); A61K 31/44 (2006.01); A61K 31/506 (2006.01); A61K 31/675 (2006.01); A61K 31/7052 (2006.01); C07D 213/80 (2006.01); C07D 401/12 (2006.01); C07D 239/47 (2006.01); C07D 413/12 (2006.01); C07D 453/02 (2006.01); A61K 31/4375 (2006.01); A61K 31/4439 (2006.01); A61K 31/4545 (2006.01); A61K 31/496 (2006.01); A61K 31/5377 (2006.01); A61K 31/541 (2006.01); A61K 31/551 (2006.01); A61K 31/553 (2006.01); A61K 31/635 (2006.01); A61K 31/706 (2006.01); C07D 405/12 (2006.01); C07F 9/58 (2006.01); C07H 19/048 (2006.01); C07F 9/6512 (2006.01); C07F 9/6558 (2006.01); C07H 13/08 (2006.01); C07H 15/26 (2006.01);
U.S. Cl.
CPC ...
C07D 213/74 (2013.01); A61K 31/4375 (2013.01); A61K 31/44 (2013.01); A61K 31/4412 (2013.01); A61K 31/4439 (2013.01); A61K 31/4545 (2013.01); A61K 31/496 (2013.01); A61K 31/506 (2013.01); A61K 31/5377 (2013.01); A61K 31/541 (2013.01); A61K 31/551 (2013.01); A61K 31/553 (2013.01); A61K 31/635 (2013.01); A61K 31/675 (2013.01); A61K 31/706 (2013.01); A61K 31/7052 (2013.01); C07D 213/80 (2013.01); C07D 239/47 (2013.01); C07D 401/12 (2013.01); C07D 405/12 (2013.01); C07D 413/12 (2013.01); C07D 453/02 (2013.01); C07F 9/587 (2013.01); C07F 9/588 (2013.01); C07F 9/65127 (2013.01); C07F 9/65583 (2013.01); C07H 13/08 (2013.01); C07H 15/26 (2013.01); C07H 19/048 (2013.01);
Abstract

There is provided a compound of formula VIIa, wherein Qrepresents —C(O)O—Calkyl, or a salt or protected derivative thereof, and other compounds that are useful in the preparation of compounds that have antiinflammatory activity (e.g., through inhibition of one or more of members of: the family of p38 mitogen-activated protein kinase enzymes; Syk kinase; and members of the Src family of tyrosine kinases) and has use in therapy, including in pharmaceutical combinations, especially in the treatment of inflammatory diseases, including inflammatory diseases of the lung, eye and intestines.

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