The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 21, 2017

Filed:

Oct. 27, 2016
Applicant:

Nuformix Limited, Cambridge, Cambridgeshire, GB;

Inventors:

Joanne Holland, Cambridge, GB;

Christopher Frampton, Stowmarket, GB;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 233/55 (2006.01); C07D 275/06 (2006.01); C07C 65/03 (2006.01); C07C 275/02 (2006.01); C07C 229/56 (2006.01);
U.S. Cl.
CPC ...
C07C 233/55 (2013.01); C07C 65/03 (2013.01); C07C 229/56 (2013.01); C07C 275/02 (2013.01); C07D 275/06 (2013.01); C07B 2200/13 (2013.01);
Abstract

New tranilast complexes and new tranilast cocrystals are disclosed. These include a 1:1 tranilast nicotinamide complex, a 1:1 tranilast nicotinamide cocrystal, a 1:1 tranilast saccharin complex, a 1:1 tranilast saccharin cocrystal, a 1:1 tranilast gentisic acid complex, a 1:1 tranilast gentisic acid cocrystal, a 1:1 tranilast salicylic acid complex, a 1:1 tranilast salicylic acid cocrystal, a 1:1 tranilast urea complex, a 1:1 tranilast urea cocrystal, a 1:1 tranilast 4-aminobenzoic acid complex, a 1:1 tranilast 4-aminobenzoic acid cocrystal, a 1:1 tranilast 2,4-dihydroxybenzoic acid complex and a 1:1 tranilast 2,4-dihydroxybenzoic acid cocrystal. Also disclosed are pharmaceutical compositions containing a tranilast complex or cocrystal of the invention and a pharmaceutically acceptable carrier. Methods of treatment using the tranilast complexes and cocrystals as well as the pharmaceutical compositions are disclosed.


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