The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 21, 2017
Filed:
Nov. 16, 2015
Applicant:
Marina Biotech, Inc., Bothell, WA (US);
Inventors:
Roger C. Adami, Bothell, WA (US);
Michael E. Houston, Jr., Sammamish, WA (US);
Rachel E. Johns, Shoreline, WA (US);
Assignee:
Marina Biotech, Inc., City of Industry, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/42 (2017.01); A61K 48/00 (2006.01); C07K 7/08 (2006.01); C07K 14/00 (2006.01); A61K 47/48 (2006.01); C12N 15/87 (2006.01); A61K 31/713 (2006.01); C12N 15/113 (2010.01);
U.S. Cl.
CPC ...
A61K 47/42 (2013.01); A61K 31/713 (2013.01); A61K 47/48046 (2013.01); A61K 47/48053 (2013.01); A61K 47/48323 (2013.01); A61K 48/0033 (2013.01); A61K 48/0041 (2013.01); C07K 7/08 (2013.01); C07K 14/00 (2013.01); C07K 14/001 (2013.01); C12N 15/113 (2013.01); C12N 15/87 (2013.01); A61K 48/00 (2013.01); C12N 2310/14 (2013.01);
Abstract
Lipopeptide compounds having a central peptide HHHHHKHHHKKKHKHKKK (SEQ ID NO:15) and a lipophilic group attached to each terminus of the peptide, and salts thereof. The lipopeptides are useful for forming pharmaceutical compositions for delivery of nucleic acid agents, such as siRNA and mdRNA agents, as well as in methods for treating the signs and symptoms of disease.