The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 21, 2017

Filed:

Oct. 06, 2015
Applicant:

Fuji Capsule Co., Ltd., Shizuoka, JP;

Inventors:

Koji Masuda, Shizuoka, JP;

Naoki Nishimura, Shizuoka, JP;

Akihiko Hayano, Shizuoka, JP;

Yoshiyuki Shimokawa, Shizuoka, JP;

Kenji Kato, Shizuoka, JP;

Assignee:

FUJI CAPSULE CO., LTD., Shizuoka, JP;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/50 (2006.01); A61K 9/48 (2006.01); A61K 31/202 (2006.01);
U.S. Cl.
CPC ...
A61K 9/4833 (2013.01); A61K 9/4825 (2013.01); A61K 9/4866 (2013.01); A61K 31/202 (2013.01);
Abstract

An object is to provide a method of manufacturing a seamless soft capsule that is enteric and excellent in formulation properties. An enteric seamless soft capsule is manufactured by the following steps (a) and (b): (a) preparing an enteric capsule shell liquid comprising gelatin and low methoxy pectin having a degree of esterification of 0 to 40% and a degree of amidation of 0 to 25%, the enteric capsule shell liquid having a viscosity at 50° C. of 60 to 127 mPa·s; and (b) encapsulating capsule fills with the enteric capsule shell liquid prepared in the step (a) by dripping. Preferably, the jelly strength of the gelatin is 180 to 330 Bloom, an aqueous solution of the low methoxy pectin at a concentration of 2 mass % has a viscosity at 35° C. of 8 to 15 mPa·s, and the enteric capsule shell liquid comprises 10 to 20 parts by mass of the low methoxy pectin per 100 parts by mass of gelatin.


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