The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 21, 2017
Filed:
Oct. 25, 2010
Applicants:
Mogens Winkel Madsen, Virum, DK;
Sune Allan Petersen, Greve, DK;
Anders Falk Vikbjerg, Greve, DK;
Inventors:
Assignee:
Bio-Bedst ApS, Hørsholm, DK;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/127 (2006.01);
U.S. Cl.
CPC ...
A61K 9/1272 (2013.01); A61K 9/1271 (2013.01);
Abstract
The present invention provides a composition comprising a sPLA2 hydrolysable liposome, an exterior solution, and an interior solution within the liposome, —wherein the concentration of osmolytes is higher in the interior solution than in the exterior solution. The composition improves storage stability of sPLA2 hydrolysable liposomes, in particular at when stored at 2-8 degrees Celsius. The liposome preferably encapsulates cisplatin. The invention also provides methods of preparing the composition of the invention.