The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 21, 2017

Filed:

May. 16, 2008
Applicants:

Anthony R. Ignagni, Oberlin, OH (US);

Raymond P. Onders, Shaker Heights, OH (US);

Inventors:

Anthony R. Ignagni, Oberlin, OH (US);

Raymond P. Onders, Shaker Heights, OH (US);

Assignee:

SYNAPSE BIOMEDICAL, INC., Oberlin, OH (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61B 10/00 (2006.01); A61B 5/0488 (2006.01); A61N 1/36 (2006.01);
U.S. Cl.
CPC ...
A61B 5/0488 (2013.01); A61N 1/3601 (2013.01);
Abstract

Described herein are methods of detecting the presence or progression of neuromuscular disorders (including ALS) based at least in part on diaphragm EMG signals taken at different points in time from the same implanted electrode(s). Signals may be used to diagnose or to monitor progression of a disorder or to track a treatment. Thus, diaphragm EMG signal may be used as a marker (e.g., a 'biomarker') for the detection or progression of a neurological disorder such as ALS. The characteristics or parameters of diaphragm EMG signals may be used to create an activity index, which may be output or compared and further analyzed. These signals may also be analyzed to show a difference between the left and right sides of the diaphragm.


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