The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 21, 2017
Filed:
May. 16, 2012
Applicants:
Randall S. Prather, Rocheport, MO (US);
Kevin D. Wells, Columbia, MO (US);
Kristin M. Whitworth, Columbia, MO (US);
Inventors:
Randall S. Prather, Rocheport, MO (US);
Kevin D. Wells, Columbia, MO (US);
Kristin M. Whitworth, Columbia, MO (US);
Assignee:
The Curators of the University of Missouri, Columbia, MO (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01K 67/027 (2006.01); C12N 15/85 (2006.01); C07K 14/705 (2006.01);
U.S. Cl.
CPC ...
A01K 67/0276 (2013.01); C12N 15/8509 (2013.01); A01K 2217/075 (2013.01); A01K 2217/15 (2013.01); A01K 2227/108 (2013.01); A01K 2267/02 (2013.01); C07K 14/7056 (2013.01); C07K 14/70596 (2013.01);
Abstract
The disclosure relates to genetically modified swine wherein at least one allele of a SIGLEC1 gene has been inactivated and/or at least one allele of a CD163 gene has been inactivated. Genetically modified swine having both alleles of the SIGLEC1 gene and/or both alleles CD 163 gene inactivated are resistant to porcine reproductive and respiratory syndrome virus (PRRSV). Methods for producing such transgenic swine are also provided.