The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 14, 2017
Filed:
Jan. 29, 2015
Applicant:
Illumina, Inc., San Diego, CA (US);
Inventor:
Stephen C. Macevicz, Cupertino, CA (US);
Assignee:
Illumina, Inc., San Diego, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2006.01); C12P 19/34 (2006.01); C07H 21/02 (2006.01); C07H 21/04 (2006.01); C07H 21/00 (2006.01); C12N 15/10 (2006.01); C12N 15/64 (2006.01); C12N 15/66 (2006.01); G06F 19/22 (2011.01);
U.S. Cl.
CPC ...
C12Q 1/6874 (2013.01); C12N 15/10 (2013.01); C12N 15/64 (2013.01); C12N 15/66 (2013.01); C12Q 1/683 (2013.01); C12Q 1/6809 (2013.01); C12Q 1/6841 (2013.01); C12Q 1/6869 (2013.01); C12Q 1/6872 (2013.01); G06F 19/22 (2013.01);
Abstract
The invention relates to methods and systems for sequencing and constructing a high resolution physical map of a polynucleotide. In accordance with the invention, nucleotide sequences are determined at the ends of restriction fragments produced by a plurality of digestions with a plurality of combinations of restriction endonucleases so that a pair of nucleotide sequences is obtained for each restriction fragment. A physical map of the polynucleotide is constructed by ordering the pairs of sequences by matching the identical sequences among the pairs.