The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 14, 2017
Filed:
Nov. 12, 2014
University-industry Foundation, Yonsei University, Seoul, KR;
SeungJoo Haam, Seoul, KR;
Yong-min Huh, Seoul, KR;
Jin-Suck Suh, Seoul, KR;
Jaemoon Yang, Seoul, KR;
Hyun-Ouk Kim, Seoul, KR;
Jihye Choi, Incheon, KR;
Eunji Jang, Seoul, KR;
Byunghoon Kang, Seoul, KR;
Ilkoo Noh, Seoul, KR;
Seo Ryung Bae, Seoul, KR;
Abstract
The present invention relates to an amphiphilic nanoparticle specific to a biomarker, and more particularly, provides an amphiphilic nanoparticle which may be used as a diagnosis or treatment-type drug or gene carrier by selectively recognizing a proteolytic enzyme specifically expressed in a cellular membrane of a specific cell, and then being bound to the proteolytic enzyme to efficiently achieve the intracellular uptake and selective cleavage. The amphiphilic nanoparticle of the present invention may be used in the diagnosis or therapy of a disease.