The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 14, 2017

Filed:

Jun. 25, 2014
Applicant:

Takeda Pharmaceutical Company Limited, Osaka-shi, Osaka, JP;

Inventors:

Mitsuhisa Yamano, Nishinomiya, JP;

Toshiaki Nagata, Ibaraki, JP;

Hideki Saitoh, Osaka, JP;

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/34 (2017.01); C08G 69/08 (2006.01); C08G 69/10 (2006.01); C08G 69/48 (2006.01); A61K 39/39 (2006.01); C08L 77/04 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C08G 69/48 (2013.01); A61K 39/39 (2013.01); A61K 47/34 (2013.01); C08G 69/08 (2013.01); C08G 69/10 (2013.01); C08L 77/04 (2013.01); A61K 2039/55555 (2013.01); A61K 2039/6093 (2013.01);
Abstract

The present invention relates to a graft copolymer of a poly(amino acid) or a salt thereof and a hydrophobic primary amine compound or a salt thereof (e.g., a graft copolymer (γ-PGA-PAE) of poly(γ-glutamic acid) (γ-PGA) and phenylalanine ethyl ester (PAE)), an ionized graft copolymer of a poly(amino acid) or a salt thereof and a hydrophobic primary amine compound or a salt thereof, nanoparticles containing the ionized graft copolymer, and a production method thereof. The nanoparticles acquired in this way are useful as an adjuvant for producing a vaccine.


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