The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 14, 2017
Filed:
Jun. 22, 2015
Siemens Healthcare Diagnostics Inc., Tarrytown, NY (US);
Manoj Sharma, Hockessin, DE (US);
Tatiana Mareeva, Haddonfield, NJ (US);
Yuriy Smirnov, Haddonfield, NJ (US);
William D. Bedzyk, Odessa, DE (US);
Zhu Teng, Garnet Valley, PA (US);
Tie Quan Wei, Wilmington, DE (US);
Siemens Healthcare Diagnostics Inc., Tarrytown, NY (US);
Abstract
Antibodies are raised against compounds of Formula (I) where Z is an immunogenic carrier. These compounds are capable of binding specifically to corresponding antibodies. The antibodies are specific for epimers of vitamin D. Antibodies in accordance with the principles described herein may be employed to minimize or eliminate 3-epimer cross-reactivity in assays for non-epimeric forms of vitamin D analytes. Over-estimation of total non-epimeric vitamin D analyte caused by the cross-reactivity of 3-epimer vitamin D with an antibody for vitamin D analyte can be substantially avoided employing, as blocking agents, antibodies prepared against immunogens that are a compound of the Formula (I) wherein Z is an immunogenic carrier.