The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 14, 2017
Filed:
Jul. 14, 2006
Arndt Dietrich, Reichenbach, DE;
Bernhard Janowski, Halle, DE;
Jörg Schäffner, Salzmünde, DE;
Ulrich Kurt Blaschke, Wiesbaden, DE;
Arndt Dietrich, Reichenbach, DE;
Bernhard Janowski, Halle, DE;
Jörg Schäffner, Salzmünde, DE;
Ulrich Kurt Blaschke, Wiesbaden, DE;
Sandoz AG, , CH;
Abstract
The present invention relates to a method for obtaining recombinant granulocyte-colony stimulating factor (G-CSF), comprising at least one cation exchange chromatography and at least one hydrophobic interaction chromatography, wherein said two chromatographic steps are immediately consecutive in optional order. In particular, the present invention relates to a method for purifying G-CSF from a mixture of G-CSF and other proteins, comprising two cation exchange chromatography steps which are conducted before and after a hydrophobic interaction chromatography, respectively.