The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 14, 2017

Filed:

Nov. 13, 2013
Applicant:

Aciex Therapeutics, Inc., Boston, MA (US);

Inventors:

Shikha P. Barman, Bedford, MA (US);

Ritesh Vasudevan Thekkedath, Boston, MA (US);

Koushik Barman, Bedford, MA (US);

Thomas Cavanagh, New Canaan, CT (US);

Tian Hao, Acton, MA (US);

Thomas Bovard Leland, Bolton, MA (US);

Assignee:

Nicox Ophthalmics, Inc., Fort Worth, TX (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/58 (2006.01); C07J 71/00 (2006.01); C07J 3/00 (2006.01); C07J 5/00 (2006.01); C07J 7/00 (2006.01); C07J 9/00 (2006.01); C07J 31/00 (2006.01); C07J 51/00 (2006.01);
U.S. Cl.
CPC ...
C07J 71/0031 (2013.01); C07J 3/005 (2013.01); C07J 5/003 (2013.01); C07J 5/0015 (2013.01); C07J 5/0038 (2013.01); C07J 5/0053 (2013.01); C07J 5/0076 (2013.01); C07J 5/0092 (2013.01); C07J 7/002 (2013.01); C07J 7/0045 (2013.01); C07J 7/0085 (2013.01); C07J 9/00 (2013.01); C07J 31/006 (2013.01); C07J 51/00 (2013.01); Y10T 428/2982 (2015.01);
Abstract

The present invention further provides method of preparing nanocrystals or microcrystals of a hydrophobic therapeutic agent such as fluticasone or triamcinolone, pharmaceutical compositions (e.g., topical or intranasal compositions) thereof and methods for treating and/or preventing the signs and/or symptoms of disorders such as blepharitis, meibomian gland dysfunction or skin inflammation or a respiratory disease (e.g., asthma).


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