The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 14, 2017
Filed:
Jan. 28, 2015
Applicant:
Glaxosmithkline Intellectual Property Development Limited, Brentford, Middlesex, GB;
Inventors:
Xiao Ding, Shanghai, CN;
Qian Liu, Shanghai, CN;
Kai Long, Shanghai, CN;
Yingxia Sang, Shanghai, CN;
Luigi Piero Stasi, Shanghai, CN;
Zehong Wan, Shanghai, CN;
Qiongfeng Xu, Shanghai, CN;
Colin Michael Edge, Stevenage, GB;
Assignee:
GlaxoSmithKline Intellectual Property Development Limited, Brentford, Middlesex, GB;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/519 (2006.01); C07D 487/04 (2006.01); A61K 31/437 (2006.01); A61K 31/4375 (2006.01); C07D 519/00 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); A61K 31/437 (2013.01); A61K 31/4375 (2013.01); C07D 519/00 (2013.01);
Abstract
The present invention relates to novel compounds that inhibit LRRK2 kinase activity, processes for their preparation, to compositions containing them and to their use in the treatment of or prevention of diseases characterized by LRRK2 kinase activity, for example Parkinson's disease, Alzheimer's disease and amyotrophic lateral sclerosis (ALS).