IDiyas

For the Inventor, By the Inventor

The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9815795 B1

PDFFull Text
Date of Patent:
Nov. 14, 2017

Filed:

May. 02, 2016

Pyridazinone and pyridone compounds

Applicant:

Biotie Therapies Corporation, Turku, FI;

Inventors:

Marjo Pihlavisto, Kaarina, FI;

David Smith, Naantali, FI;

Auni Juhakoski, Raisio, FI;

Ferenc Fulop, Szeged, HU;

Laszlo Lazar, Szeged, HU;

Istvan Szatmari, Szeged, HU;

Ferenc Miklos, Szeged, HU;

Zsolt Szakonyi, Szeged, HU;

Lorand Kiss, Szeged, HU;

Marta Palko, Szeged, HU;

Assignee:

BIOTIE THERAPIES CORPORATION, Turku, FI;

Attorney:

Birch, Stewart, Kolasch & Birch, LLP

Primary Examiner:

Jeffrey H Murray

Int. Cl.
CPC ...
A61K 31/497 (2006.01); A01N 43/40 (2006.01); A61K 31/44 (2006.01); C07D 403/00 (2006.01); C07D 405/00 (2006.01); C07D 409/00 (2006.01); C07D 401/00 (2006.01); C07D 237/24 (2006.01); C07D 405/14 (2006.01); C07D 401/04 (2006.01); C07D 403/04 (2006.01); C07D 405/04 (2006.01); C07D 409/04 (2006.01); C07D 413/04 (2006.01); C07D 401/14 (2006.01); A61K 31/50 (2006.01); A61K 31/501 (2006.01); A61K 31/5377 (2006.01); A61K 45/06 (2006.01); C07D 237/16 (2006.01); C07D 403/12 (2006.01); C07D 403/14 (2006.01); G01N 33/50 (2006.01); A61K 31/4439 (2006.01); A61K 31/496 (2006.01); C07C 57/15 (2006.01);
U.S. Cl.
CPC ...
C07D 237/24 (2013.01); A61K 31/4439 (2013.01); A61K 31/496 (2013.01); A61K 31/50 (2013.01); A61K 31/501 (2013.01); A61K 31/5377 (2013.01); A61K 45/06 (2013.01); C07C 57/15 (2013.01); C07D 237/16 (2013.01); C07D 401/04 (2013.01); C07D 401/14 (2013.01); C07D 403/04 (2013.01); C07D 403/12 (2013.01); C07D 403/14 (2013.01); C07D 405/04 (2013.01); C07D 405/14 (2013.01); C07D 409/04 (2013.01); C07D 413/04 (2013.01); G01N 33/502 (2013.01);
Abstract

The invention relates to pyridazinone and pyridone compounds having formula (I) or (I'), and pharmaceutically acceptable salts, hydrates, and solvates thereof wherein R/Rand X and Xare as defined in the claims. The invention further relates to their use as inhibitors of copper-containing amine oxidases. The present invention also relates to the preparation of the aforementioned compounds and to pharmaceutical compositions comprising as an active ingredient(s) one or more of the aforementioned compounds, pharmaceutically acceptable salts, hydrates, or solvates thereof.

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