The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 14, 2017

Filed:

Feb. 26, 2016
Applicant:

Boehringer Ingelheim International Gmbh, Ingelheim am Rhein, DE;

Inventors:

Mandar Deodhar, New South Wales, AU;

Alison Dorothy Findlay, New South Wales, AU;

Jonathan Stuart Foot, New South Wales, AU;

Wolfgang Jarolimek, New South Wales, AU;

Ian Alexander Mcdonald, New South Wales, AU;

Alan Duncan Robertson, New South Wales, AU;

Craig Ivan Turner, New South Wales, AU;

Assignee:

Boehringer Ingelheim International GmbH, Ingelheim am Rhein, DE;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/165 (2006.01); C07C 321/26 (2006.01); C07C 235/46 (2006.01); C07C 323/62 (2006.01); C07C 237/30 (2006.01); C07C 311/37 (2006.01); C07C 323/63 (2006.01); C07C 311/29 (2006.01); C07C 311/16 (2006.01);
U.S. Cl.
CPC ...
C07C 321/26 (2013.01); C07C 235/46 (2013.01); C07C 237/30 (2013.01); C07C 311/16 (2013.01); C07C 311/29 (2013.01); C07C 311/37 (2013.01); C07C 323/62 (2013.01); C07C 323/63 (2013.01);
Abstract

The present invention is related to the preparation and pharmaceutical use of substituted 3-haloallylamine derivatives as SSAO/VAP-1 inhibitors having the structure of Formula I, as defined in the specification: The invention also relates to methods of using compounds of Formula I, or pharmaceutically acceptable salt or derivatives thereof, for the treatment of a variety of indications, e.g., inflammatory diseases, ocular diseases, fibrotic diseases, diabetes-induced diseases and cancer.


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