The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 14, 2017

Filed:

Mar. 04, 2014
Applicant:

Biocon Limited, Bangalore, IN;

Inventors:

Kothakonda Kiran Kumar, Karnataka, IN;

Chandrashekar Aswathanarayanappa, Bannerghatta Road, IN;

Dharshan Jakkali Chandregowda, Chikamaghur, IN;

Chandrasekhar Duvva, Andhra Pradesh, IN;

Venkata Srinivas Pullela, Andhra Pradesh, IN;

Assignee:

Biocon Limited, Bangalore, IN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 213/08 (2006.01); C07C 231/12 (2006.01); C07C 227/06 (2006.01);
U.S. Cl.
CPC ...
C07C 213/08 (2013.01); C07C 227/06 (2013.01); C07C 231/12 (2013.01);
Abstract

The present disclosure relates to processes for the preparation of 2-amino-1,3-propane diol compounds and their hydrochloride salts. Particularly, the present disclosure relates to processes for synthesizing 2-amino-2-(2-(4-octylphenyl)ethyl)-1,3-propanediol and its hydrochloride salt 2-amino-2-(2-(4-octylphenyl)ethyl)-1,3-propanediol hydrochloride respectively. The said process is safe, commercially feasible for large-scale synthesis and has improved efficacy along with many other advantages. The present disclosure also relates to the novel polymorphs of 2-amino-1,3-propane diol compound and its hydrochloride salt, where in 2-amino-1,3-propane diol compound is 2-amino-2-(2-(4-octylphenyl)ethyl)-1,3-propanediol, and its hydrochloride salt is 2-amino-2-(2-(4-octylphenyl)ethyl)-1,3-propanediol hydrochloride.


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