The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 14, 2017

Filed:

Mar. 14, 2014
Applicant:

President and Fellows of Harvard College, Cambridge, MA (US);

Inventors:

Jene A. Golovchenko, Lexington, MA (US);

Bo Lu, Cambridge, MA (US);

Aaron T. Kuan, Cambridge, MA (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
B05D 1/34 (2006.01); C25F 3/14 (2006.01); B01D 67/00 (2006.01); C25F 3/00 (2006.01); B01D 69/02 (2006.01);
U.S. Cl.
CPC ...
B05D 1/34 (2013.01); B01D 67/0034 (2013.01); B01D 67/0062 (2013.01); B01D 67/0065 (2013.01); B01D 69/02 (2013.01); C25F 3/00 (2013.01); C25F 3/14 (2013.01); B01D 2323/35 (2013.01); B01D 2325/02 (2013.01);
Abstract

In a method for forming nanopores, two opposing surfaces of a membrane are exposed to an electrically conducting liquid environment. A nanopore nucleation voltage pulse, having a first nucleation pulse amplitude and duration, is applied between the two membrane surfaces, through the liquid environment. After applying the nanopore nucleation voltage pulse, the electrical conductance of the membrane is measured and compared to a first prespecified electrical conductance. Then at least one additional nanopore nucleation voltage pulse is applied between the two membrane surfaces, through the liquid environment, if the measured electrical conductance is no greater than the first prespecified electrical conductance.


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