The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 14, 2017
Filed:
Aug. 20, 2015
Saitama Medical University, Iruma-gun, Saitama, JP;
Japan As Represented BY the Director-general of National Institute of Infectious Diseases, Tokyo, JP;
Nof Corporation, Tokyo, JP;
Toshitaka Akatsuka, Saitama, JP;
Tetsuya Uchida, Tokyo, JP;
Maiko Taneichi, Tokyo, JP;
Ai Mikuma, Kawasaki, JP;
Shoichi Yokoyama, Kawasaki, JP;
Saitama Medical University, Iruma, JP;
Japan as represented by the Director-General of National Institute of Infectious Diseases, Tokyo, JP;
NOF Corporation, Tokyo, JP;
Abstract
The invention provides a method for the prophylaxis or treatment of hepatitis C in a mammal with a peptide-bound liposome wherein the peptide contains a partial amino acid sequence having a length of not less than 9 amino acids in the amino acid sequence of hepatitis C virus NS3 protein, has a length of 9 to 11 amino acids, and is capable of inducing cytotoxic T lymphocytes; the liposome contains a phospholipid containing an acyl group having 14 to 24 carbon atoms and one unsaturated bond or a hydrocarbon group having 14 to 24 carbon atoms and one unsaturated bond, and a liposome stabilizer; and the peptide is bound to the surface of the liposome. The invention also provides a cytotoxic T lymphocyte activator containing the peptide-bound liposome, as well as a hepatitis C virus vaccine.