The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 14, 2017

Filed:

Jan. 02, 2014
Applicant:

Celltrion, Inc., Incheon, KR;

Inventors:

Young Jun Park, Incheon, KR;

Jin-kyo Jeong, Incheon, KR;

Young Mi Choi, Incheon, KR;

Minseob Lee, Incheon, KR;

Yeon Jung Kim, Incheon, KR;

Kyoung Suk Kim, Incheon, KR;

Joon hun Choi, Incheon, KR;

Jin Seo Lee, Incheon, KR;

Eun Joo Cho, Incheon, KR;

Hyunnam Song, Incheon, KR;

Sung Jun Park, Incheon, KR;

Jong-hyoup Lee, Incheon, KR;

Matthew Sangyup Lee, Incheon, KR;

In-Suk Lee, Incheon, KR;

Joon woo Kim, Incheon, KR;

Seung Suh Hong, Incheon, KR;

Assignee:

CELLTRION, INC., Incheon, KR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/48 (2006.01); C07D 403/12 (2006.01); C07D 207/416 (2006.01); C07K 16/30 (2006.01); A61K 38/08 (2006.01);
U.S. Cl.
CPC ...
A61K 47/48715 (2013.01); A61K 38/08 (2013.01); A61K 47/48415 (2013.01); A61K 47/48438 (2013.01); A61K 47/48484 (2013.01); A61K 47/48569 (2013.01); A61K 47/48584 (2013.01); C07D 207/416 (2013.01); C07D 403/12 (2013.01); C07K 16/30 (2013.01);
Abstract

The present invention relates to an antibody-linker-drug conjugate in which an antibody and a cytotoxic drug are conjugated through an enzyme cleavable peptide linker capable of directly binding to a lysine residue of an antibody, a preparation method therefor, and


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