The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 14, 2017

Filed:

Nov. 17, 2011
Applicants:

Stéphanie Barrere, Vendemian, FR;

Joël Nargeot, Montpellier, FR;

Bernard Lebleu, Montpellier, FR;

Prisca Boisguerin, Le Grand-du-Roi, FR;

Christophe Piot, Saint Clement de Riviere, FR;

Inventors:

Stéphanie Barrere, Vendemian, FR;

Joël Nargeot, Montpellier, FR;

Bernard Lebleu, Montpellier, FR;

Prisca Boisguerin, Le Grand-du-Roi, FR;

Christophe Piot, Saint Clement de Riviere, FR;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 45/06 (2006.01); A61K 38/08 (2006.01); A61K 38/17 (2006.01); C07K 14/47 (2006.01); A61K 38/10 (2006.01);
U.S. Cl.
CPC ...
A61K 38/1709 (2013.01); A61K 38/08 (2013.01); A61K 38/10 (2013.01); A61K 45/06 (2013.01); C07K 14/4747 (2013.01);
Abstract

The invention relates to fragments of the Death-Domain Associated protein (DAXX protein) and of the Fas-Associated Death Domain protein (FADD protein) that inhibit cell apoptosis, in particular cell apoptosis mediated by the Fas receptor. The invention also relates to derivatives of said anti-apoptotic fragments, conjugates comprising said fragments, pharmaceutical compositions comprising said fragments, and to the medical applications of said fragments, derivatives, conjugates, and pharmaceutical compositions thereof in the treatment or prevention of diseases and conditions associated with apoptosis.


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