The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 14, 2017
Filed:
Aug. 07, 2013
Applicant:
Polyphor Ag, Allschwil, CH;
Inventors:
Assignee:
Polyphor AG, Allschwil, CH;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/12 (2006.01); C07K 5/12 (2006.01); C07K 7/64 (2006.01); A61K 45/06 (2006.01); A61K 31/405 (2006.01); A61K 31/496 (2006.01); A61K 31/7036 (2006.01); A61K 31/7052 (2006.01); A61K 31/407 (2006.01); A61K 47/48 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
A61K 38/12 (2013.01); A61K 31/405 (2013.01); A61K 31/407 (2013.01); A61K 31/496 (2013.01); A61K 31/7036 (2013.01); A61K 31/7052 (2013.01); A61K 45/06 (2013.01); C07K 5/12 (2013.01); C07K 7/64 (2013.01); A61K 38/00 (2013.01); A61K 47/48407 (2013.01);
Abstract
A novel combination comprising a β-hairpin peptidomimetic of the formula cyclo(-Thr-Trp-Ile-Dab-Orn-Dab-Dab-Trp-Dab-Dab-Ala-Ser-Pro-Pro) (I), and a further compound with antibiotic activity, that enable therapeutic control of specific bacterial infections in human or animals at doses of the individual compounds lower than either of the compounds administered alone. The combination can be used as a medicament to treat e.g. skin or soft tissue infections; eye, ear, blood stream, or intra-abdominal infections; infections related to respiratory diseases, to bone diseases, to cardiovascular diseases, to genitourinal diseases, or to gastrointestinal diseases.