The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 14, 2017
Filed:
May. 20, 2016
Plexxikon Inc., Berkeley, CA (US);
Prabha N. Ibrahim, Mountain View, CA (US);
Chao Zhang, Moraga, CA (US);
Wayne Spevak, Berkeley, CA (US);
Jiazhong Zhang, Foster City, CA (US);
Guoxian Wu, Palo Alto, CA (US);
Jack Lin, Hercules, CA (US);
Hanna Cho, Oakland, CA (US);
Marika Nespi, Berkeley, CA (US);
Songyuan Shi, Fremont, CA (US);
Todd Ewing, Walnut Creek, CA (US);
Ying Zhang, Fremont, CA (US);
Gideon Bollag, Orinda, CA (US);
Plexxikon Inc., Berkeley, CA (US);
Abstract
The present disclosure provides methods of treating a subject suffering from or at risk of a BRAF V600 mutation or BRAF fusion mutation related disease or condition, without activating the MAPK pathway or inducing expression of MAPK pathway genes in cells harboring wild-type BRAF.