The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 14, 2017
Filed:
Nov. 21, 2016
Universite Pierre ET Marie Curie (Paris 6), Paris, FR;
Universite DE Liege, Angelur, BE;
Adrien Pagano, Limours, FR;
Karla Hadot, Limours, FR;
Michele Reboud-Ravaux, Paris, FR;
Chahrazade Yerroum-El Amri, Ermont, FR;
Xiao Tan, Villejuif, FR;
Lixian Qin, Paris, FR;
Maurice Pagano, Limours, FR;
Alain Hovnanian, Vincennes, FR;
Laetitia Furio, Montrouge, FR;
Bernard Pirotte, Oupeye, BE;
UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6), Paris, FR;
UNIVERSITE DE LIEGE, Angleur, BE;
Abstract
A compound of formula (I-1) wherein n equals 0 or 1, Z represents O or S, R1 represents one group chosen among the group consisting of hydrogen, C1-C7 alkyl, substituted, or not, by a halogen, a hydroxyl or a —O—R12 group, wherein R12 is a C1-C7 alkyl, a group —CH—O—CO—R5 wherein R5 is chosen among a hydrogen atom and a C1-C7 alkyl, substituted or not by at least one halogen, a group —O—R13, wherein R13 is chosen among hydrogen and a C1-C7 alkyl, an amine or a —CH-amine, R'1 represents a group chosen among hydrogen and —O—R14, wherein R14 is chosen among hydrogen and a C1-C7 alkyl, and R2 is chosen among the group consisting of a C1-C7 alkyl, a C3-C6 cycloalkyl, an aryl group, and an heteroaryl group for the treatment of pathologies involving excess activity of at least one member of the kallikrein family.