The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 14, 2017

Filed:

Mar. 28, 2012
Applicants:

Samir Mitragotri, Santa Barbara, CA (US);

Byeong Hee Hwang, Goleta, CA (US);

Nishit Doshi, Mountain View, CA (US);

Kenneth Tsai, Houston, TX (US);

Russell Lebovitz, San Diego, CA (US);

Inventors:

Samir Mitragotri, Santa Barbara, CA (US);

Byeong Hee Hwang, Goleta, CA (US);

Nishit Doshi, Mountain View, CA (US);

Kenneth Tsai, Houston, TX (US);

Russell Lebovitz, San Diego, CA (US);

Assignees:

THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, Oakland, CA (US);

DX BIOSCIENCES, INC., San Diego, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61B 5/00 (2006.01); C07K 1/14 (2006.01); A61K 9/06 (2006.01); A61K 31/205 (2006.01); A61K 31/765 (2006.01); A61K 9/00 (2006.01); C07K 16/18 (2006.01); C12N 1/06 (2006.01);
U.S. Cl.
CPC ...
A61B 5/443 (2013.01); A61K 9/0014 (2013.01); A61K 9/06 (2013.01); A61K 31/205 (2013.01); A61K 31/765 (2013.01); C07K 1/14 (2013.01); A61K 9/0009 (2013.01); C07K 16/18 (2013.01); C07K 2317/52 (2013.01); C07K 2317/94 (2013.01); C12N 1/06 (2013.01);
Abstract

Solubilizing compositions are provided that include a 3-(alkyl dimethyl ammonia) propane sulfonate zwitterionic surfactant and a polyethylene glycol alkyl ether nonionic surfactant, provided that the zwitterionic surfactant and the nonionic surfactant are not simultaneously and respectively 3-(decyl dimethyl ammonia) propane sulfonate and polyoxyethylene (4) lauryl ether. Also provided are methods for solubilizing cells and/or tissue of a subject in vivo and methods for recovering proteins from skin cells of a subject in vivo using the solubilizing compositions.


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