The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 07, 2017

Filed:

Jul. 02, 2015
Applicant:

Universite DE Reims Champagne-ardenne, Reims, FR;

Inventors:

Vincent Vuiblet, Chenay, FR;

Olivier Piot, Cormontreuil, FR;

Philippe Rieu, Merfy, FR;

Michael Fere, Reims, FR;

Cyril Gobinet, Athies-Sous-Laon, FR;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 21/35 (2014.01); G01N 21/3563 (2014.01); G01N 33/50 (2006.01); G01N 21/31 (2006.01);
U.S. Cl.
CPC ...
G01N 21/3563 (2013.01); G01N 33/5091 (2013.01); G01N 2021/3196 (2013.01); G01N 2021/3595 (2013.01); G01N 2201/10 (2013.01); G01N 2201/129 (2013.01);
Abstract

A method for detecting and quantifying fibrosis, which involves at least; positioning a non-colored fixed tissue sample on a support; carrying out infrared acquisition, by scanning, of points of the sample; converting the infrared spectrum produced by each acquired point into at least one spectral image; carrying out a digital processing operation on the spectral image by distinguishing between at least physiological collagen and pathological collagen from fibrosis, attributing, to each point, a spectral class defined by an algorithm classifying the spectra according to the spectral similarities % thereof, then attributing a status to each class by statistically comparing with a digital model of spectra; quantifying the relative surface area occupied by the points of each status; and recording the result.


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