The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 07, 2017
Filed:
Jun. 19, 2015
Applicant:
Somagenics, Inc., Santa Cruz, CA (US);
Inventors:
Sergei A. Kazakov, San Jose, CA (US);
Catharina Casper-Lindley, Santa Cruz, CA (US);
Anne Dallas, Santa Cruz, CA (US);
Heini Ilves, Santa Cruz, CA (US);
Brian H. Johnston, Scotts Valley, CA (US);
Assignee:
SOMAGENICS, INC., Santa Cruz, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6851 (2013.01);
Abstract
Disclosed herein are compositions and methods for the processing, amplification and detection of polynucleotides using target-specific oligonucleotides (TSOs). Hybridization of TSOs to target polynucleotides guides target processing into and purification of small target fragments that then can be amplified and detected with high sensitivity and reproducibility. The method is specifically beneficial for highly degraded polynucleotides found in biological samples.