The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 07, 2017

Filed:

Nov. 20, 2014
Applicants:

National University Corporation Tottori University, Tottori-shi, Tottori, JP;

The Chemo-sero-therapeutic Research Institute, Kumamoto-shi, Kumamoto, JP;

Inventor:

Takafumi Nakamura, Yonago, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 417/00 (2006.01); C12N 7/00 (2006.01); A61K 48/00 (2006.01); C12N 15/09 (2006.01); A61K 35/768 (2015.01);
U.S. Cl.
CPC ...
C12N 7/00 (2013.01); A61K 35/768 (2013.01); A61K 48/00 (2013.01); C12N 15/09 (2013.01); C12N 2710/24121 (2013.01); C12N 2710/24132 (2013.01); C12N 2710/24162 (2013.01); C12N 2710/24171 (2013.01);
Abstract

This invention provides a vaccinia virus that grows specifically in a cancer cell and damages such cancer cell and the use of such virus for treatment of cancer. Such mitogen-activated protein kinase-dependent vaccinia virus strain lacks functions of vaccinia virus growth factor (VGF) and O1L, it does not grow in normal cells but grows specifically in cancer cells, and it has oncolytic properties that specifically damage cancer cells.


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