The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 07, 2017

Filed:

Aug. 03, 2015
Applicant:

Eisai R&d Management Co., Ltd., Tokyo, JP;

Inventors:

Toshio Imai, Kyoto, JP;

James Bradford Kline, Morgantown, PA (US);

Tetsu Kawano, Kobe, JP;

Luigi Grasso, Bryn Mawr, PA (US);

Yoshimasa Sakamoto, Nishinomiya, JP;

Jared Spidel, Downingtown, PA (US);

Miyuki Nishimura, Kobe, JP;

Kenzo Muramoto, Tsukuba, JP;

Tatsuo Horizoe, Moriya, JP;

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/24 (2006.01); G01N 33/68 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/24 (2013.01); G01N 33/6863 (2013.01); A61K 2039/505 (2013.01); C07K 2317/24 (2013.01); C07K 2317/33 (2013.01); C07K 2317/34 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01); G01N 2333/521 (2013.01);
Abstract

The present invention relates to novel humanized, chimeric and murine antibodies that have binding specificity for the human CC chemokine ligand 20 (CCL20). The present invention further relates to heavy chains and light chains of said antibodies. The invention also relates to isolated nucleic acids, recombinant vectors and host cells that comprise a sequence which encodes a heavy chain and/or a light chain of said antibodies, and to a method of preparing said antibodies. The anti-CCL20 antibodies of the invention can be used in therapeutic applications to treat, for example, inflammatory and autoimmune disorders and cancer.


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