The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 07, 2017
Filed:
Feb. 17, 2017
Applicant:
Rutgers, the State University of New Jersey, New Brunswick, NJ (US);
Inventors:
Richard H. Ebright, New Brunswick, NJ (US);
Yon W. Ebright, New Brunswick, NJ (US);
Yu Feng, New Brunswick, NJ (US);
David Degen, New Brunswick, NJ (US);
Assignee:
Rutgers, the State University of New Jersey, New Brunswick, NJ (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 11/02 (2006.01); C07K 1/06 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 11/02 (2013.01); C07K 1/062 (2013.01); A61K 38/00 (2013.01);
Abstract
The invention provides compounds of formula (I): and salts thereof, wherein X and Y have any of the values defined herein. The compounds inhibit bacterial RNA polymerase, inhibit bacterial growth, and have applications in, analysis of RNA polymerase structure and function, control of bacterial gene expression, control of bacterial growth, antibacterial chemistry, antibacterial therapy, and drug discovery.