The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 07, 2017

Filed:

Sep. 05, 2014
Applicant:

Sun Yat-sen University Cancer Center, Guangzhou, CN;

Inventors:

Musheng Zeng, Guangzhou, CN;

Xing Zhang, Guangzhou, CN;

Jun Wang, Guangzhou, CN;

Guokai Feng, Guangzhou, CN;

Mengqing Zhang, Guangzhou, CN;

Qian Zhong, Guangzhou, CN;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); A61K 38/03 (2006.01); A61K 38/08 (2006.01); A61K 38/10 (2006.01); A61K 51/08 (2006.01); C07K 7/06 (2006.01); C07K 7/08 (2006.01); C07K 7/00 (2006.01); A61K 47/48 (2006.01); A61K 49/00 (2006.01);
U.S. Cl.
CPC ...
C07K 7/06 (2013.01); A61K 47/48246 (2013.01); A61K 49/0056 (2013.01); A61K 51/08 (2013.01); A61K 51/088 (2013.01); C07K 7/08 (2013.01); A61K 38/00 (2013.01);
Abstract

A tumor-targeting peptide is disclosed. This tumor-targeting peptide comprises a typical motif with the general formula of: XX(Y/F) (D/E) (D/E) XX. The motif is selectively connected with 1-3 amino acids at the C-terminal and/or N-erminal. X represents any one of the twenty natural amino acids or the D type amino acids. The present invention also discloses that the peptide can not only target tumor vessels and tumor cells but also penetrate them and thus can be applied in tumor diagnosis and therapy.


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