The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 07, 2017
Filed:
Nov. 07, 2014
Applicant:
Beijing Zhibo Bio-medical Technology Co.,ltd, Beijing, CN;
Inventors:
Mengchao Cui, Beijing, CN;
Chunping Lin, Beijing, CN;
Boli Liu, Beijing, CN;
Yuzhi Guo, Beijing, CN;
Zhiyong Zhang, Beijing, CN;
Assignees:
BEIJING ZHIBO BIO-MEDICAL TECHNOLOGY CO., LTD, Beijing, CN;
Other;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 417/04 (2006.01); C07D 413/04 (2006.01); C07D 263/57 (2006.01); C07D 277/66 (2006.01); A61K 51/04 (2006.01); A61K 49/10 (2006.01);
U.S. Cl.
CPC ...
C07D 417/04 (2013.01); A61K 49/10 (2013.01); A61K 51/0453 (2013.01); A61K 51/0455 (2013.01); C07D 263/57 (2013.01); C07D 277/66 (2013.01); C07D 413/04 (2013.01);
Abstract
A fluorinated 2-arylbenzo heterocyclic compound with high affinity to Aβ plaques and containing a chiral side chain substituent, has a general formula (I) as follows: F isF orF; Ris NHCHor N(CH). The compound of the present invention has high affinity to Aβ plaques and can be used to make appropriate radioactive nuclide labeling probes for early diagnosis of AD.