The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 07, 2017

Filed:

Jul. 22, 2014
Applicants:

Les Laboratoires Servier, Suresnes, FR;

Vernalis (R&d) Ltd, Winnersh, GB;

Inventors:

James Edward Paul Davidson, Great Shelford, GB;

James Brooke Murray, Linton, GB;

I-Jen Chen, Cambridge, GB;

Claire Walmsley, Ely, GB;

Mark Dodsworth, Fulbourn, GB;

Johannes W. G. Meissner, Linton, GB;

Paul Brough, Haverhill Suffolk, GB;

Imre Fejes, Budapest, HU;

János Tatai, Budapest, HU;

Miklós Nyerges, Leányfalu, HU;

András Kotschy, Törökbálint, HU;

Zoltán Szlávik, Budapest, HU;

Olivier Geneste, Rueil-Malmaison, FR;

Arnaud Le Tiran, Croissy sur Seine, FR;

Thierry Le Diguarher, Saint Denis de l'Hôtel, FR;

Jean-Michel Henlin, Suresnes, FR;

Jérôme-Benoît Starck, Rueil Malmaison, FR;

Anne-Françoise Guillouzic, Nanterre, FR;

Guillaume De Nanteuil, Suresnes, FR;

Assignees:

LES LABORATOIRES SERVIER, Suresnes, FR;

VERNALIS (R&D) LTD, Winnersh, GB;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4155 (2006.01); C07D 401/14 (2006.01); C07D 405/14 (2006.01); A61K 31/4725 (2006.01); C07D 409/14 (2006.01); C07D 471/04 (2006.01); A61K 31/496 (2006.01); A61K 31/497 (2006.01); A61K 31/5377 (2006.01); A61K 31/675 (2006.01); A61K 45/06 (2006.01); A61N 5/10 (2006.01); C07D 417/14 (2006.01); C07F 9/6561 (2006.01);
U.S. Cl.
CPC ...
C07D 401/14 (2013.01); A61K 31/4725 (2013.01); A61K 31/496 (2013.01); A61K 31/497 (2013.01); A61K 31/5377 (2013.01); A61K 31/675 (2013.01); A61K 45/06 (2013.01); A61N 5/10 (2013.01); C07D 405/14 (2013.01); C07D 409/14 (2013.01); C07D 417/14 (2013.01); C07D 471/04 (2013.01); C07F 9/65616 (2013.01);
Abstract

Compounds of formula (I): wherein Het, R, R, R, R, R, R, T, p, p', q, and q′ are as defined in the description. Medicinal products containing the same which are useful in treating pathologies involving a deficit in apoptosis, such as cancer, auto-immune diseases, and diseases of the immune system.


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