The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 07, 2017
Filed:
Mar. 13, 2015
Applicant:
Takeda Pharmaceutical Company Limited, Osaka, JP;
Inventors:
Masatoshi Yamada, Osaka, JP;
Sayuri Hirano, Osaka, JP;
Ryoji Tsuruoka, Osaka, JP;
Mitsuhisa Yamano, Osaka, JP;
Assignee:
Takeda Pharmaceutical Company Limited, Osaka, JP;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 401/04 (2006.01); C07D 211/60 (2006.01); C07D 211/78 (2006.01); C07F 17/02 (2006.01); B01J 31/24 (2006.01); C07F 9/50 (2006.01); C07F 15/00 (2006.01); B01J 31/22 (2006.01);
U.S. Cl.
CPC ...
C07D 401/04 (2013.01); B01J 31/2226 (2013.01); B01J 31/2295 (2013.01); B01J 31/2409 (2013.01); B01J 31/2452 (2013.01); C07D 211/60 (2013.01); C07D 211/78 (2013.01); C07F 9/5027 (2013.01); C07F 15/0046 (2013.01); C07F 17/02 (2013.01); B01J 2231/645 (2013.01); B01J 2531/0205 (2013.01); B01J 2531/0263 (2013.01); B01J 2531/0266 (2013.01); B01J 2531/821 (2013.01); B01J 2531/822 (2013.01); B01J 2531/824 (2013.01); B01J 2531/827 (2013.01); B01J 2531/842 (2013.01); B01J 2540/225 (2013.01); C07B 2200/07 (2013.01);
Abstract
The present invention provides a method of efficiently producing an optically active 6-(3-aminopiperidin-1-yl)-2,4-dioxo -1,2,3,4-tetrahydropyrimidine derivative. The optically active piperidine-3-carboxamide or a derivative thereof, which is obtained by subjecting 1,4,5,6-tetrahydropyridine -3-carboxamide or a derivative thereof to an asymmetric reduction in the presence of a catalyst, is used as an intermediate.