The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 07, 2017

Filed:

Jan. 13, 2012
Applicants:

Paul S. Cederna, Milan, MI (US);

Melanie G. Urbanchek, Ann Arbor, MI (US);

David C. Martin, Lincoln University, PA (US);

Inventors:

Paul S. Cederna, Milan, MI (US);

Melanie G. Urbanchek, Ann Arbor, MI (US);

David C. Martin, Lincoln University, PA (US);

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61N 1/00 (2006.01); A61N 1/05 (2006.01); A61F 2/72 (2006.01); A61L 27/34 (2006.01); A61F 2/08 (2006.01);
U.S. Cl.
CPC ...
A61N 1/0551 (2013.01); A61F 2/0811 (2013.01); A61F 2/72 (2013.01); A61L 27/34 (2013.01); A61L 2430/32 (2013.01);
Abstract

The present disclosure provides a regenerative peripheral nerve interface (RPNI) for a subject comprising an insulating substrate, at least one metallic electrode deposited onto the insulating substrate forming a thin-film array; a portion of the at least one metallic electrode surface having a layer of a first conductive polymer and a layer of decellularized small intestinal submucosa (SIS) coating a portion of the electrode, wherein a second conductive polymer is electrochemically polymerized through the SIS to form the regenerative peripheral nerve interface. The present disclosure also provides that a layer of muscle tissue contacts the regenerative peripheral nerve interface.


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