The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 07, 2017

Filed:

Aug. 11, 2008
Applicants:

Michael L. Lovett, Medford, MA (US);

Xianyan Wang, Acton, MA (US);

Christopher M. Cannizzaro, Washington, DC (US);

Gordana Vunjak-novakovic, New York, NY (US);

David L. Kaplan, Concord, MA (US);

Inventors:

Michael L. Lovett, Medford, MA (US);

Xianyan Wang, Acton, MA (US);

Christopher M. Cannizzaro, Washington, DC (US);

Gordana Vunjak-Novakovic, New York, NY (US);

David L. Kaplan, Concord, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61F 2/06 (2013.01); A61L 27/36 (2006.01); A61L 27/22 (2006.01); A61F 2/08 (2006.01); A61L 27/26 (2006.01); A61F 2/07 (2013.01); A61F 2/82 (2013.01);
U.S. Cl.
CPC ...
A61L 27/227 (2013.01); A61F 2/08 (2013.01); A61L 27/26 (2013.01); A61F 2/07 (2013.01); A61F 2/82 (2013.01); A61L 27/3604 (2013.01); D10B 2211/22 (2013.01); Y10T 428/13 (2015.01);
Abstract

Described are tubular silk fibroin compositions and methods for their manufacture and use. Tubular compositions as described herein can be produced in a range of high burst strengths, can easily be made in a range of inner diameters, can be derivatized with functional moieties, and can be produced in a range of permeabilities suitable for particularized uses. In one aspect, the tubular compositions can be used in the repair or replacement of damaged or diseased blood vessels, including, but not limited to vessels smaller than about 6 mm.


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