The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 07, 2017

Filed:

Aug. 12, 2014
Applicants:

Tokai Pharmaceuticals, Inc., Boston, MA (US);

University of Washington, Seattle, WA (US);

University of Maryland, Baltimore, Baltimore, MD (US);

Inventors:

Vincent C. O. Njar, Glen Burnie, MD (US);

Amina Zoubeidi, Vancouver, CA;

Karen Ferrante, Boston, MA (US);

Eva Corey, Seattle, WA (US);

Douglas Jacoby, Wellesley, MA (US);

Assignees:

Tokai Pharmaceuticals, Inc., Boston, MA (US);

University of Washington, Seattle, WA (US);

University of Maryland, Baltimore, Baltimore, MD (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/58 (2006.01); C07J 43/00 (2006.01); C12Q 1/68 (2006.01);
U.S. Cl.
CPC ...
A61K 31/58 (2013.01); C07J 43/003 (2013.01); C12Q 1/6886 (2013.01); C12Q 2600/156 (2013.01); C12Q 2600/158 (2013.01);
Abstract

Described herein are methods and compositions for the treatment of prostate cancer in a subject in need thereof. The prostate cancer may be a castration resistant and an androgen receptor antagonist-resistant prostate cancer. The methods may comprise administering to the subject a CYP17-lyase inhibitor of Formula II.


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