The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 07, 2017
Filed:
Jan. 26, 2016
Fundación Centro Nacional DE Investigaciones Oncologicas Carlos Iii, Madrid, ES;
Joaquín Pastor Fernández, Madrid, ES;
Rosa María Álvarez Escobar, Madrid, ES;
Rosario Concepción Riesco Fagundo, Madrid, ES;
Ana Belén García García, Madrid, ES;
Antonio Rodríguez Hergueta, Madrid, ES;
Jose Ignacio Martín Hernando, Madrid, ES;
Carmen Blanco Aparicio, Madrid, ES;
David Álvaro Cebrián Muñoz, Madrid, ES;
Abstract
There is provided compounds of formula I, wherein R1, R, R, R, X, Y, Z, Rand ring A/B have meanings given in the description, and pharmaceutically-acceptable esters, amides, solvates or salts thereof, which compounds are useful in the treatment of diseases in which inhibition of a protein or lipid kinase (e.g. PI3-K, particularly class I PI3K, PIM family kinase and/or mTOR) is desired and/or required, and particularly in the treatment of cancer. The invention also relates to combinations containing such compounds.